The association between BMI and mortality using early adulthood BMI as an instrumental variable for midlife BMI
نویسندگان
چکیده
منابع مشابه
The association between BMI and mortality using offspring BMI as an indicator of own BMI: large intergenerational mortality study
OBJECTIVES To obtain valid estimates of the association between body mass index (BMI) and mortality by using offspring BMI as an instrumental variable for own BMI. DESIGN Cohort study based on record linkage, with 50 years of follow-up for mortality. Associations of offspring BMI with all cause and cause specific maternal and paternal mortality were estimated as hazard ratios per standard dev...
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Evidence Various systematic reviews of observational studies in the general population evaluate all-cause mortality and BMI.1-10 • The review with the most studies1 (97 studies, 2.88 million participants) found the following relative risks (RRs) compared with normal BMI (18.5-24.9 kg/m2): -overweight (25.0-29.9 kg/m2), RR = 0.94; -obese, grade I (30.0-35.0 kg/m2), RR = 0.95; and -obese, grade I...
متن کاملSources of heterogeneity in studies of the BMI-mortality association
BACKGROUND To date, the amount of heterogeneity among studies of the body mass index-mortality association attributable to differences in the age distribution and length of follow-up has not been quantified. Therefore, we wanted to quantify the amount of heterogeneity attributable to age and follow-up in results of studies on the body mass index-mortality relation. METHODS We used optima of t...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-29089-z